Register for my Obagi online shop. Use discount code OBAGI20 for 20% off. Register Now

POLYNUCLEOTIDES

Regenerate and Rejuvenate Skin With Natural-Looking Results In Grange Park, North London

Polynucleotides are injectable skin treatments designed to support repair, improve hydration, and enhance skin quality with minimal downtime.

  • Doctor-led treatment
  • Safety-first approach
  • Subtle, natural-looking skin rejuvenation

Welcome to Dr Clare Aesthetics Polynucleotide Treatments

At Dr Clare Aesthetics clinic in Grange Park, North London, I offer the latest innovation in skin rejuvenation - Plinest polynucleotide treatments. This modern therapy harnesses the power of regenerative medicine to revitalise your skin on a cellular level.

AT A GLANCE

Quick View

Benefits

  • Rejuvenates & improves quality of the skin, making it brighter & healthier looking
  • Restores the skin's texture, elasticity, and promotes hydration
  • Minimal downtime

Areas

  • Under-eye
  • Face
  • Neck
  • Décolletage
  • Hands
  • Other areas of the body after suitability assessment, like stomach and buttocks

Procedure Time

Typically 20-30 minutes per session

Pain Level

Minimal discomfort with topical anaesthetic cream

Results

  • Improvements appear gradually over several weeks
  • Maximum benefits seen from 3—4 treatments, 3 weeks apart

Duration

  • Long term skin rejuvenation
  • Maintenance is advised every 4-6 months

Cost

From £300 per treatment

What Are Polynucleotides?

A Doctor-Led Approach to Skin Regeneration

Polynucleotides are naturally occurring molecules found in our DNA and RNA. You can think of them as tiny building blocks that help the cells in our body to work properly. Polynucleotides have amazing benefits for our body including skin rejuvenation, wound healing and natural regeneration.

When injected into the skin, polynucleotides stimulate fibroblasts—the cells responsible for producing collagen and elastin. This leads to a gradual improvement in skin quality, texture, and overall appearance. The range of benefits includes:

Improved skin hydration and moisture retention Enhanced skin elasticity and firmness Smoother skin texture with reduced fine lines Reduced inflammation Increased collagen production Brighter, healthier-looking skin

TREATMENT AREAS

Explore Common Polynucleotide Treatment Areas in Grange Park

Plinest polynucleotides is a safe and effective treatment with minimal downtime. It's suitable for all skin types and can be used to address a wide range of concerns. It is a favoured treatment at my Grange Park clinic due to the results being natural-looking and long-lasting.

Following assessment, treatment may be offered where skin quality, hydration, and resilience can be improved.

Under-eye and facial skin rejuvenation treatment area

Under-Eye & Face Area

Supports smoother, healthier-looking skin where dullness, fine lines, and reduced elasticity are concerns.

Book Your Appointment
Neck polynucleotide treatment area

Neck

Helps improve crepey texture and skin quality in the neck, where signs of ageing and dehydration can develop early.

Book Your Appointment
Decolletage polynucleotide treatment area

Decolletage

Targets sun-exposed chest skin to support hydration, texture, and a smoother overall appearance.

Book Your Appointment
Hands polynucleotide treatment area

Hands

Rejuvenates the skin on the hands where thinning and dryness can make skin look older than the face.

Book Your Appointment
Acne polynucleotide treatment area

Acne

Helps improve the appearance of acne-prone skin by supporting hydration, texture, and overall skin health.

Book Your Appointment
Hairloss polynucleotide treatment area

Hair loss

Improve scalp skin health, to reduce hair loss and promote hair growth with denser results.

Book Your Appointment

HOW POLYNUCLEOTIDES WORK

How Polynucleotides Support Healthier-Looking Skin

Polynucleotides are designed to improve skin condition from within by supporting regeneration, hydration, and tissue quality.

01

Purified Polynucleotides Are Placed Precisely

Treatment is administered to carefully selected points based on your anatomy and skin concerns, with a doctor-led focus on safety and suitability.

02

Skin Repair and Hydration Support Begin

Polynucleotides help create an environment that supports tissue repair, hydration balance, and improved skin comfort.

03

Gradual Improvement in Texture and Elasticity

Over the following weeks, many patients notice smoother texture, better elasticity, and a more rested skin appearance.

TREATMENT JOURNEY

Your Polynucleotides Timeline

A simple guide to how treatment is usually planned and when skin quality changes are often noticed.

Session 1

Initial Treatment

What happens: Treatment is performed after consultation, assessment, and consent.

Effect: Early hydration and tissue support begin, with gradual changes to follow.

Week 3-4

Second Session

What happens: A follow-up session is often recommended to reinforce treatment response.

Effect: Skin support is strengthened for more visible improvements in quality.

Weeks 6-8

Improvement Window

What happens: Regenerative processes continue gradually within the skin.

Effect: Skin may appear smoother, fresher, and more elastic.

~6 Months

Maintenance Review

What happens: Progress is reviewed and maintenance timing is discussed.

Effect: Ongoing maintenance can help preserve treatment benefits.

WHY CHOOSE US

Why Choose Dr Clare Aesthetics for Polynucleotide Treatments in North London?

Doctor-led care focused on safety, skin quality, and realistic treatment planning.

Medical-Led Expertise

My medical qualifications support my treatments, ensuring safe, professional care.

Personalised Treatment Plans

Every treatment is tailored to individual needs, focusing on achieving natural-looking, rejuvenating results.

Advanced, Reputable Treatments

My clinic offers high-quality Plinest Polynucleotide treatments, known for improving skin elasticity, collagen production, and overall skin health

Convenient North London Location

Our clinic is conveniently located in North London, making it easy for you to access quality, cutting edge polynucleotide treatments.

Patient Testimonials

What Our Clients Say

Every treatment starts with a thorough, doctor-led consultation to understand your goals, assess your skin, and create a safe plan tailored to you.

POLYNUCLEOTIDES FAQ

Frequently Asked Questions

Polynucleotide treatments offer a range of benefits, including improved skin elasticity, increased collagen production, enhanced skin hydration, reduced inflammation, and a more even skin tone. It can also address specific concerns like fine lines, acne scars, and dark circles.

Plinest is the brand of polynucleotide that I use in the clinic. Plinest is a gel-like substance that's injected into the skin. Once injected, the polynucleotides begin to take effect, encouraging fibroblast activity and promoting the regeneration of skin tissue. This leads to a gradual improvement in skin quality, texture, and overall appearance.

Yes, Polynucleotides can be used to rejuvenate the skin on the neck, décolletage, inner arms, hands, thighs, knees, scalp and other regions where skin quality and elasticity need improvement.

Yes, Polynucleotides are a safe and well-tolerated treatment. It is made from naturally occurring molecules and has minimal side effects.

If you are allergic to fish, treatment with polynucleotides would not be recommended. You should be advised to get a hyaluronic-based skin booster treatment such as Profhilo or Sunekos instead.

Yes. A consultation is essential to assess your concerns, review medical history, and decide whether polynucleotides are suitable for you.

No. Polynucleotides are used to improve skin quality and support regeneration. Dermal fillers are primarily used to add volume or structure.

The number of treatments needed can vary depending on your individual goals and the condition of your skin. Most often I advise 3-4 initial treatments spaced 3 weeks apart with maintenance treatment following this, every 6 months. I will recommend a personalised treatment plan during your consultation.

The results of Polynucleotides are long-lasting, but the exact duration can vary depending on individual factors such as age, skin condition, and lifestyle. Typically, you can expect the results to last between 6-9 months.

Downtime is usually minimal. Mild redness, swelling, tenderness, or occasional bruising can occur and typically settles quickly. Most people are able to resume their usual activities immediately.

Most patients find treatment tolerable. A topical numbing cream can be used to help minimise discomfort.

After a thorough consultation to assess your individual needs, I will carefully inject the product into the targeted areas using a very fine needle. The procedure is relatively quick and straightforward. You will experience minimal discomfort as I will use a topical numbing cream beforehand. You may be left with small bumps under the skin and some redness, which will typically disappear within a few hours.

  • Refrain from touching the treated area for at least 6 hours.
  • Avoid makeup in the treated area for 12 hours.
  • Avoid strenuous exercise, heat exposure, and alcohol for 24 hours.
  • Use sunscreen daily and follow any product advice given at your appointment.
  • Contact the clinic if you have unexpected symptoms or concerns.

Pricing depends on the treatment area and product plan. You can discuss exact costs during consultation, or contact the clinic for current pricing.

Ready to Improve Your Skin Quality With Polynucleotides?

Book your doctor-led appointment in Grange Park, North London, and receive a personalised plan for healthier, smoother, naturally refreshed skin.

Fully Insured & Accredited